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Query: MMACHC

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MMACHC 0 -2.082 -0.480 0.370

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MMACHC Phosphorylation S245 -0.926 -1.526 _LALLGLAQPSEKPSS(ph)PSPDLPFTTPAPK_
MMACHC Phosphorylation S247 -1.686 _LALLGLAQPSEKPSSPS(ph)PDLPFTTPAPK_

Background Information for MMACHC:


Pubmed-MMACHC »
Uniprot-MMACHC »
Biogrid-MMACHC »
ProteomicsDB-MMACHC »

Tumorportal-MMACHC »
COSMIC-MMACHC »
GenomeRNAi-MMACHC »
Genecards-MMACHC


Protein-protein Interactions for MMACHC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SELENBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MMACHC
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring MMACHC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MMACHC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Disease phenotype HOMOCYSTEINEMIA HOMOCYSTEINEMIA Database 0.53
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006767 water-soluble vitamin metabolic process Database 0.27
Category members GO Category GO:0006766 vitamin metabolic process Database 0.23
Category members GO Category GO:0031419 cobalamin binding Database 0.06
Category members GO Category GO:0009235 cobalamin metabolic process Database 0
Category members GO Category GO:0009236 cobalamin biosynthetic process Database 0


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