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Query: MLLT6

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MLLT6 0 -1.584 0.789 0.246

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MLLT6 Phosphorylation S261 -1.204 _KRPESPPS(ph)ILTPPVVPTADK_
MLLT6 Phosphorylation S258 -1.415 -1.306 _KRPES(ph)PPSILTPPVVPTADK_

Background Information for MLLT6:


Pubmed-MLLT6 »
Uniprot-MLLT6 »
Biogrid-MLLT6 »
ProteomicsDB-MLLT6 »

Tumorportal-MLLT6 »
COSMIC-MLLT6 »
GenomeRNAi-MLLT6 »
Genecards-MLLT6


Protein-protein Interactions for MLLT6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DOT1L Cat. description Hein, Mann, Cell 2015
Category members IP bait MLLT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait YEATS4 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLLT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MLLT6
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring MLLT6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MLLT6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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