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Query: MLLT10

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MLLT10 0 -0.866 -0.450 0.720

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MLLT10 Phosphorylation S689 -0.717 -0.869 _S(ph)PVSSLQIR_

Background Information for MLLT10:


Pubmed-MLLT10 »
Uniprot-MLLT10 »
Biogrid-MLLT10 »
ProteomicsDB-MLLT10 »

Tumorportal-MLLT10 »
COSMIC-MLLT10 »
GenomeRNAi-MLLT10 »
Genecards-MLLT10


Protein-protein Interactions for MLLT10
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C9orf126;SCAI Cat. description Hein, Mann, Cell 2015
Category members IP bait DOT1L Cat. description Hein, Mann, Cell 2015
Category members IP bait MLLT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NAA50 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMPO Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2I Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF526 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLLT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PMF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCP10L Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MLLT10
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_PHD-finger IPR019787 0.91


Protein complexes (CORUM database) featuring MLLT10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MLLT10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members Disease phenotype Precursor_T-cell_acute_lymphoblastic_leukemia Precursor T-cell acute lymphoblastic leukemia Database 0


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