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Query: MIS18A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MIS18A 0 1.228 -1.160 1.800

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MIS18A Ubiquitylation K232 -0.835 -0.536 _LSFATCK(gl)S_
MIS18A Ubiquitylation K33 -1.048 _CSDSSLLGK(gl)R_
MIS18A Ubiquitylation K203 -0.546 _VEIEK(gl)SLTQMEDVLK_
MIS18A Ubiquitylation K213 -0.035 _SLTQMEDVLK(gl)ALQMK_
MIS18A Ubiquitylation K218 -1.139 _ALQMK(gl)LWEAESK_

Background Information for MIS18A:





Protein-protein Interactions for MIS18A

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CAV3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CENPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CEP170 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HJURP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MIS18A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCAPH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OIP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPICE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM150A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MIS18A

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring MIS18A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MIS18A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members GO Category GO:0034080 CENP-A containing nucleosome assembly at centromere Database 4.75
Category members Pathway Pathway_1281 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 0 4.19
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members GO Category GO:0007059 chromosome segregation Database 0.13
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members GO Category GO:0044030 regulation of DNA methylation Database 0.05
Category members GO Category GO:0008150 biological_process Database 0


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