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Query: METTL2B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
METTL2B 0 -0.786 0.220 -0.610
METTL2B 0 -0.786 0.630 0.130

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
METTL2B Phosphorylation S4 0.542 0.916 _(ac)AGS(ph)YPEGAPAILADK_
METTL2B Phosphorylation T154 -0.081 0.346 _TQT(ph)PPVEENVTQK_
METTL2B Ubiquitylation K151 -2.244 _SLEHK(gl)TQTPPVEENVTQK_

Background Information for METTL2B:


Pubmed-METTL2B »
Uniprot-METTL2B »
Biogrid-METTL2B »
ProteomicsDB-METTL2B »

Tumorportal-METTL2B »
COSMIC-METTL2B »
GenomeRNAi-METTL2B »
Genecards-METTL2B


Protein-protein Interactions for METTL2B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MLF1IP Cat. description Hein, Mann, Cell 2015
Category members IP bait C7orf52 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait METTL2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in METTL2B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Methyltransf_11 IPR013216 0.2
Category members SAM-dependent_MTases-like IPR029063 0.04
Category members UbiE/COQ5_MeTrFase IPR004033 0
Category members Methyltransf_12 IPR013217 0
Category members MeTrfase IPR026113 0


Protein complexes (CORUM database) featuring METTL2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring METTL2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_137 KEGG_HISTIDINE_METABOLISM 0 0
Category members Pathway Pathway_154 KEGG_TYROSINE_METABOLISM 0 0
Category members Pathway Pathway_299 KEGG_SELENOAMINO_ACID_METABOLISM 0 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0008168 methyltransferase activity Database 0
Category members GO Category GO:0030488 tRNA methylation Database 0


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