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Query: ME2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ME2 1 1.643 1.604 -1.411 0.751 0.699

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for ME2:


Pubmed-ME2 »
Uniprot-ME2 »
Biogrid-ME2 »
ProteomicsDB-ME2 »

Tumorportal-ME2 »
COSMIC-ME2 »
GenomeRNAi-ME2 »
Genecards-ME2


Protein-protein Interactions for ME2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TMEM184A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ME2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Malic_OxRdtase IPR001891 0
Category members Malic_N_dom IPR012301 0
Category members Malic_NAD-bd IPR012302 0


Protein complexes (CORUM database) featuring ME2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ME2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0051287 NAD binding Database 1.6
Category members Pathway Pathway_16 KEGG_PYRUVATE_METABOLISM 0 1.34
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0009055 electron carrier activity Database 0.02
Category members GO Category GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity Database 0
Category members GO Category GO:0006108 malate metabolic process Database 0
Category members GO Category GO:0008948 oxaloacetate decarboxylase activity Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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