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Query: MAN2C1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAN2C1 0 -0.317 0.000 0.800

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAN2C1 Ubiquitylation K767 -1.117 _K(gl)PVLGQAGTLAVGTEGGLR_

Background Information for MAN2C1:


Pubmed-MAN2C1 »
Uniprot-MAN2C1 »
Biogrid-MAN2C1 »
ProteomicsDB-MAN2C1 »

Tumorportal-MAN2C1 »
COSMIC-MAN2C1 »
GenomeRNAi-MAN2C1 »
Genecards-MAN2C1


Protein-protein Interactions for MAN2C1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SART1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGTB Cat. description Hein, Mann, Cell 2015
Category members IP bait C22orf33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC20B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCMT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNCA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VWA5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAN2C1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glyco_hydro_38_N IPR000602 0
Category members Gal_mutarotase_SF_dom IPR011013 0
Category members Glyco_hydro/deAcase_b/a-brl IPR011330 0
Category members Glyco_hydro_38_C IPR011682 0
Category members Glyco_hydro_38_cen IPR015341 0
Category members Glyco_hydro_57/38_cen IPR028995 0


Protein complexes (CORUM database) featuring MAN2C1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MAN2C1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0006013 mannose metabolic process Database 0.04
Category members Pathway Pathway_129 KEGG_OTHER_GLYCAN_DEGRADATION 0 0
Category members GO Category GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds Database 0
Category members GO Category GO:0004559 alpha-mannosidase activity Database 0
Category members GO Category GO:0015923 mannosidase activity Database 0
Category members GO Category GO:0030246 carbohydrate binding Database 0


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