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Query: LYPLA1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LYPLA1 0 -0.118

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LYPLA1 Ubiquitylation K138 -0.118 _ALIDQEVK(gl)NGIPSNR_

Background Information for LYPLA1:


Pubmed-LYPLA1 »
Uniprot-LYPLA1 »
Biogrid-LYPLA1 »
ProteomicsDB-LYPLA1 »

Tumorportal-LYPLA1 »
COSMIC-LYPLA1 »
GenomeRNAi-LYPLA1 »
Genecards-LYPLA1


Protein-protein Interactions for LYPLA1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CTSO Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FCF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEAD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LYPLA1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PLipase/COase/thioEstase IPR003140 0
Category members AB_hydrolase_3 IPR013094 0
Category members AB_hydrolase IPR029058 0


Protein complexes (CORUM database) featuring LYPLA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LYPLA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members Pathway Pathway_276 KEGG_GLYCEROPHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_438 REACTOME_ENOS_ACTIVATION_AND_REGULATION 0 0
Category members GO Category GO:0002084 protein depalmitoylation Database 0
Category members GO Category GO:0004622 lysophospholipase activity Database 0
Category members GO Category GO:0006631 fatty acid metabolic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0008474 palmitoyl-(protein) hydrolase activity Database 0
Category members GO Category GO:0042997 negative regulation of Golgi to plasma membrane protein transport Database 0
Category members GO Category GO:0046209 nitric oxide metabolic process Database 0
Category members GO Category GO:0050999 regulation of nitric-oxide synthase activity Database 0


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