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Query: LRRC8E

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LRRC8E 0 -1.471 1.180 -0.970

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LRRC8E Ubiquitylation K175 -0.790 -0.681 _ALSEVSGENQK(gl)GPAATER_

Background Information for LRRC8E:





Protein-protein Interactions for LRRC8E

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DLK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FCGR3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC8B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC8E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NMUR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGIR Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LRRC8E

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Leu-rich_rpt_typical-subtyp IPR003591 0.57
Category members Leu-rich_rpt IPR001611 0.32
Category members LRR_protein-8_N IPR021040 0.03


Protein complexes (CORUM database) featuring LRRC8E

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LRRC8E

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67


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