bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »
bioLOGIC Data

bioLOGIC Data


Exact search

Query: LRRC8A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LRRC8A 0 -1.529 -0.310 -0.480 -0.421 -1.303
LRRC8A 0 -1.529 -0.310 -0.480 -0.331

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LRRC8A Ubiquitylation K241 0.439 0.087 _EGEQAK(gl)ALFEK_
LRRC8A Ubiquitylation K246 -0.231 _ALFEK(gl)VK_

Background Information for LRRC8A:





Protein-protein Interactions for LRRC8A

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait C3AR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DLK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FADS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR77 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GYPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IPPK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC8B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM30B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UPK1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LRRC8A

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Leu-rich_rpt_typical-subtyp IPR003591 0.57
Category members Leu-rich_rpt IPR001611 0.32
Category members LRR_protein-8_N IPR021040 0.03


Protein complexes (CORUM database) featuring LRRC8A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LRRC8A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Disease phenotype Autosomal_agammaglobulinemia Autosomal agammaglobulinemia Database 0
Category members GO Category GO:0002329 pre-B cell differentiation Database 0


© Copyright Svejstrup Laboratory 2015