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Query: LRR1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LRR1 0 -1.426 0.010 -0.750

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LRR1 Ubiquitylation K78 -0.398 -1.028 _FVDEGK(gl)ATVR_
LRR1 Ubiquitylation K154 -0.718 _GCNVDTPVSTLTPVK(gl)TSEFENFK_
LRR1 Ubiquitylation K162 -0.973 _TSEFENFK(gl)TK_

Background Information for LRR1:


Pubmed-LRR1 »
Uniprot-LRR1 »
Biogrid-LRR1 »
ProteomicsDB-LRR1 »

Tumorportal-LRR1 »
COSMIC-LRR1 »
GenomeRNAi-LRR1 »
Genecards-LRR1


Protein-protein Interactions for LRR1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait COPS7A Cat. description Hein, Mann, Cell 2015
Category members IP bait LRR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYL12A;MYL12B Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RAPGEF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait COPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RELL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB38 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LRR1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Leu-rich_rpt_typical-subtyp IPR003591 0.57
Category members Leu-rich_rpt IPR001611 0.32


Protein complexes (CORUM database) featuring LRR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LRR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0016853 isomerase activity Database 0.37
Category members GO Category GO:0016567 protein ubiquitination Database 0.07


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