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Query: LRIG3

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LRIG3 0 1.473 -0.670 0.400

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LRIG3 Phosphorylation S1073 0.575 0.498 _AHS(ph)SPDLDSGSEEDGK_

Background Information for LRIG3:


Pubmed-LRIG3 »
Uniprot-LRIG3 »
Biogrid-LRIG3 »
ProteomicsDB-LRIG3 »

Tumorportal-LRIG3 »
COSMIC-LRIG3 »
GenomeRNAi-LRIG3 »
Genecards-LRIG3


Protein-protein Interactions for LRIG3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GAL3ST1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRIG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMPRSS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LRIG3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ig-like_dom IPR007110 0.6
Category members Leu-rich_rpt_typical-subtyp IPR003591 0.57
Category members Ig_sub IPR003599 0.43
Category members Leu-rich_rpt IPR001611 0.32
Category members Immunoglobulin IPR013151 0.23
Category members Cys-rich_flank_reg_C IPR000483 0.21
Category members Ig_sub2 IPR003598 0.21
Category members Ig_I-set IPR013098 0.13


Protein complexes (CORUM database) featuring LRIG3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LRIG3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0007275 multicellular organismal development Database 0.31


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