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Query: LRBA

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LRBA 2 4.830 -0.630 0.460 -0.806
LRBA 2 4.830 -0.630 0.460 0.507

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LRBA Phosphorylation S1488 2.977 1.630 _SAAKS(ph)PVDIVTGGISPVR_
LRBA Phosphorylation S1261 0.534 0.505 _LELKAS(ph)PNVEAPQPHR_
LRBA Ubiquitylation K2268 -1.318 -0.187 _DLSKPIGALNPK(gl)R_
LRBA Phosphorylation S10 -1.001 -0.916 _(ac)ASEDNRVPS(ph)PPPTGDDGGGGGR_
LRBA Ubiquitylation K2024 0.249 _TAVEHATDEDILAK(gl)GK_
LRBA Ubiquitylation K2260 -0.351 _DLSK(gl)PIGALNPK_

Background Information for LRBA:


Pubmed-LRBA »
Uniprot-LRBA »
Biogrid-LRBA »
ProteomicsDB-LRBA »

Tumorportal-LRBA »
COSMIC-LRBA »
GenomeRNAi-LRBA »
Genecards-LRBA


Protein-protein Interactions for LRBA
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CXorf48 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKFZp686O24166 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DLK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPHA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM196A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GYPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PVR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LRBA
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members BEACH_dom IPR000409 0
Category members ConA-like_lec_gl_sf IPR008985 0
Category members DUF1088 IPR010508 0


Protein complexes (CORUM database) featuring LRBA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LRBA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members Disease phenotype Common_variable_immunodeficiency Common variable immunodeficiency Database 0
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0008150 biological_process Database 0


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