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Query: LLGL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LLGL1 0 -1.267 0.510 -0.650 -0.591 -2.332

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LLGL1 Ubiquitylation K19 0.826 0.830 _LK(gl)QELFAFNK_
LLGL1 Ubiquitylation K17 0.617 _EK(gl)LKQELFAFNK_

Background Information for LLGL1:


Pubmed-LLGL1 »
Uniprot-LLGL1 »
Biogrid-LLGL1 »
ProteomicsDB-LLGL1 »

Tumorportal-LLGL1 »
COSMIC-LLGL1 »
GenomeRNAi-LLGL1 »
Genecards-LLGL1


Protein-protein Interactions for LLGL1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LLGL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PARD6A Cat. description Hein, Mann, Cell 2015
Category members IP bait PARD6B Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKCI Cat. description Hein, Mann, Cell 2015
Category members IP bait KBTBD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PARD6B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKCZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LLGL1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members Lethal2_giant IPR000664 0
Category members LLGL2 IPR013577 0


Protein complexes (CORUM database) featuring LLGL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 959 LLGL1-PAR-6B-PRKCI complex Database 0.01


Categories featuring LLGL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0030866 cortical actin cytoskeleton organization Database 0.89
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0000137 Golgi cis cisterna Database 0.33
Category members GO Category GO:0005097 Rab GTPase activator activity Database 0.3
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0032851 positive regulation of Rab GTPase activity Database 0.21
Category members GO Category GO:0006887 exocytosis Database 0.2
Category members GO Category GO:0007409 axonogenesis Database 0.13
Category members GO Category GO:0030864 cortical actin cytoskeleton Database 0.06
Category members GO Category GO:0035748 myelin sheath abaxonal region Database 0.06
Category members GO Category GO:0032588 trans-Golgi network membrane Database 0.05
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0006893 Golgi to plasma membrane transport Database 0


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