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Query: LIN28B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LIN28B 0 -1.545 0.030 0.570 -1.232 -0.383

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LIN28B Phosphorylation S203 -0.212 -0.288 _EVGGGHGCTS(ph)PPFPQEAR_
LIN28B Phosphorylation T202 -0.245 -0.339 _EVGGGHGCT(ph)SPPFPQEAR_

Background Information for LIN28B:


Pubmed-LIN28B »
Uniprot-LIN28B »
Biogrid-LIN28B »
ProteomicsDB-LIN28B »

Tumorportal-LIN28B »
COSMIC-LIN28B »
GenomeRNAi-LIN28B »
Genecards-LIN28B


Protein-protein Interactions for LIN28B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SURF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3HAV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LIN28B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NA-bd_OB-fold IPR012340 4.37
Category members Znf_CCHC IPR001878 1.51
Category members CSP_DNA-bd IPR002059 0.04
Category members Cold_shock_prot IPR011129 0.04


Protein complexes (CORUM database) featuring LIN28B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LIN28B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_65 PID_MYC_ACTIV_PATHWAY 0 1.08
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members Disease phenotype Neuroblastoma Neuroblastoma Database 0.08
Category members GO Category GO:0031054 pre-miRNA processing Database 0.01
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0010587 miRNA catabolic process Database 0
Category members GO Category GO:0031123 RNA 3'-end processing Database 0


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