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Query: LIMA1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LIMA1 2 4.274 0.510 -0.720 0.394 -0.758 0.133 -0.288 0.193

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LIMA1 Phosphorylation S736 1.527 _S(ph)QDVELWEGEVVK_
LIMA1 Phosphorylation S696 0.978 _EGHSLEMENENLVENGADS(ph)DEDDNSFLK_
LIMA1 Phosphorylation S234 1.170 0.188 _IS(ph)ENSYSLDDLEIGPGQLSSSTFDSEKNESR_
LIMA1 Phosphorylation S619 -0.096 0.127 _TVS(ph)PPIRK_
LIMA1 Phosphorylation S141 -0.032 0.091 _LRS(ph)PPEALVQGR_
LIMA1 Phosphorylation S384 -0.108 0.021 _ASSLSESS(ph)PPK_
LIMA1 Phosphorylation S500 0.041 -0.064 _ETPHS(ph)PGVEDAPIAK_
LIMA1 Phosphorylation T497 0.258 -0.079 _ET(ph)PHSPGVEDAPIAK_
LIMA1 Phosphorylation S375 -0.152 _SEVQQPVHPKPLSPDS(ph)R_
LIMA1 Phosphorylation S379 -0.062 -0.213 _ASS(ph)LSESS(ph)PPK_
LIMA1 Phosphorylation S383 -0.220 _ASS(ph)LSES(ph)SPPK_
LIMA1 Phosphorylation S372 -0.472 -0.444 _SEVQQPVHPKPLS(ph)PDSR_
LIMA1 Ubiquitylation K289 0.981 _YQAAVSK(gl)QSSSTNYTNELK_
LIMA1 Ubiquitylation K308 1.903 _ASGGEIK(gl)IHK_
LIMA1 Ubiquitylation K757 0.263 _ELSVEEQIK(gl)R_

Background Information for LIMA1:





Protein-protein Interactions for LIMA1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GAK Cat. description Hein, Mann, Cell 2015
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CC Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED10 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VCL Cat. description Hein, Mann, Cell 2015
Category members IP bait BCL7C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GOPC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GSTK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC39 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LSP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEXN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHG6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFP41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LIMA1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_LIM IPR001781 0


Protein complexes (CORUM database) featuring LIMA1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LIMA1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members Pathway Pathway_466 PID_ECADHERIN_STABILIZATION_PATHWAY 0 1.4
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0051015 actin filament binding Database 0.99
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0051017 actin filament bundle assembly Database 0.47
Category members GO Category GO:0030835 negative regulation of actin filament depolymerization Database 0.4
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0001725 stress fiber Database 0.04
Category members GO Category GO:0003785 actin monomer binding Database 0
Category members GO Category GO:0031529 ruffle organization Database 0


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