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Query: LARS2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LARS2 0 1.578 0.710 -0.650 1.178 -0.803 0.598 0.605

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for LARS2:


Pubmed-LARS2 »
Uniprot-LARS2 »
Biogrid-LARS2 »
ProteomicsDB-LARS2 »

Tumorportal-LARS2 »
COSMIC-LARS2 »
GenomeRNAi-LARS2 »
Genecards-LARS2


Protein-protein Interactions for LARS2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACAA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ACSM5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP5D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCKDHB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BPNT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BSG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf85 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DUSP22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NIT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDHB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUCLG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TGOLN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YBEY Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LARS2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Val/Leu/Ile-tRNA-synth_edit IPR009008 0.08
Category members V/L/I-tRNA-synth_anticodon-bd IPR013155 0.08
Category members aa-tRNA-synth_Ia IPR002300 0
Category members tRNAsynth_1a_anticodon-bd IPR009080 0
Category members Methionyl/Leucyl_tRNA_Synth IPR015413 0


Protein complexes (CORUM database) featuring LARS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LARS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_202 REACTOME_TRNA_AMINOACYLATION 0 1.34
Category members GO Category GO:0006418 tRNA aminoacylation for protein translation Database 0.91
Category members Pathway Pathway_409 KEGG_AMINOACYL_TRNA_BIOSYNTHESIS 0 0.82
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0004812 aminoacyl-tRNA ligase activity Database 0.41
Category members GO Category GO:0002161 aminoacyl-tRNA editing activity Database 0.23
Category members GO Category GO:0004823 leucine-tRNA ligase activity Database 0.15
Category members GO Category GO:0006429 leucyl-tRNA aminoacylation Database 0.15
Category members Disease phenotype Perrault_syndrome Perrault syndrome Database 0.11
Category members Pathway Pathway_47 KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS 0 0.09
Category members Pathway Pathway_203 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION 0 0


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