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Query: KNTC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KNTC1 0 -0.156 0.710 -0.410 0.293 0.500 -0.856

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KNTC1 Ubiquitylation K185 0.138 _IQQAIENVDFSTAK(gl)K_
KNTC1 Phosphorylation S1034 -0.231 _HKPGS(ph)TPEPIAAEVR_
KNTC1 Phosphorylation T1035 -0.279 _HKPGST(ph)PEPIAAEVR_
KNTC1 Ubiquitylation K186 -0.295 _IQQAIENVDFSTAKK(gl)_
KNTC1 Ubiquitylation K43 -0.569 _ISSEK(gl)ASLNPK_
KNTC1 Ubiquitylation K1948 -0.580 _EGMIK(gl)GLWK_
KNTC1 Ubiquitylation K859 -0.734 _EVNLLNK(gl)EIMR_
KNTC1 Ubiquitylation K1307 -0.854 _LFGETTLVK(gl)SR_
KNTC1 Ubiquitylation K1076 -0.855 _ALK(gl)DGNIK_
KNTC1 Ubiquitylation K2145 -1.032 _EFGILAKTK(gl)_
KNTC1 Ubiquitylation K239 -1.141 _WEPDSSK(gl)K_
KNTC1 Ubiquitylation K240 -1.141 _WEPDSSK(gl)K_
KNTC1 Ubiquitylation K949 -1.252 _LALQEEPDHSKEGK(gl)_
KNTC1 Ubiquitylation K870 -1.284 _YILK(gl)QDVPSSLEDALK_

Background Information for KNTC1:


Pubmed-KNTC1 »
Uniprot-KNTC1 »
Biogrid-KNTC1 »
ProteomicsDB-KNTC1 »

Tumorportal-KNTC1 »
COSMIC-KNTC1 »
GenomeRNAi-KNTC1 »
Genecards-KNTC1


Protein-protein Interactions for KNTC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTR5 Cat. description Hein, Mann, Cell 2015
Category members IP bait NIPSNAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPIRE2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZW10 Cat. description Hein, Mann, Cell 2015
Category members IP bait BSG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C12orf49 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf75 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDNRB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPHA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL13RA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC15A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM108 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM171 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM206 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KNTC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members PAH IPR003822 0
Category members Quino_amine_DH_bsu IPR011044 0


Protein complexes (CORUM database) featuring KNTC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KNTC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0000922 spindle pole Database 0.35
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members GO Category GO:0007093 mitotic cell cycle checkpoint Database 0.27
Category members GO Category GO:0007096 regulation of exit from mitosis Database 0.07
Category members GO Category GO:0005828 kinetochore microtubule Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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