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Query: KLC4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KLC4 0 2.634 -0.530 1.140

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KLC4 Phosphorylation S566 0.644 0.850 _RSS(ph)ELLVR_
KLC4 Phosphorylation S565 0.634 _RS(ph)SELLVR_
KLC4 Phosphorylation S460 -1.421 0.032 _VSS(ph)PTVNTTLR_
KLC4 Phosphorylation S590 -0.041 -0.055 _AAS(ph)LNYLNQPSAAPLQVSR_
KLC4 Phosphorylation Y593 -0.025 _RAASLNY(ph)LNQPSAAPLQVSR_

Background Information for KLC4:


Pubmed-KLC4 »
Uniprot-KLC4 »
Biogrid-KLC4 »
ProteomicsDB-KLC4 »

Tumorportal-KLC4 »
COSMIC-KLC4 »
GenomeRNAi-KLC4 »
Genecards-KLC4


Protein-protein Interactions for KLC4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIF5B Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC4 Cat. description Hein, Mann, Cell 2015
Category members IP bait AZIN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRNA9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COG6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIF2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KPTN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYCL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUP43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRAK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KLC4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR_1 IPR001440 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members TPR_2 IPR013105 0.45
Category members Rabaptin_Rab5-bd_dom IPR015390 0.21
Category members Kinesin_light IPR002151 0.16
Category members Pentatricopeptide_repeat IPR002885 0


Protein complexes (CORUM database) featuring KLC4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KLC4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0005874 microtubule Database 1.21
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members Pathway Pathway_1314 REACTOME_KINESINS 0 0.32
Category members GO Category GO:0005871 kinesin complex Database 0.27
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07


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