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Query: KIFC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KIFC1 0 -1.080 -0.640 0.260 0.028 0.119 -0.257

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KIFC1 Phosphorylation S6 -0.299 0.109 _(ac)MDPQRS(ph)PLLEVK_
KIFC1 Ubiquitylation K107 -1.040 _NQK(gl)PVPAVPVQK_

Background Information for KIFC1:





Protein-protein Interactions for KIFC1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIFC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait PARD6B Cat. description Hein, Mann, Cell 2015
Category members IP bait PDLIM5 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM188A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUP50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KIFC1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Kinesin_motor_dom IPR001752 0


Protein complexes (CORUM database) featuring KIFC1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KIFC1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0007018 microtubule-based movement Database 0.75
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members GO Category GO:0005819 spindle Database 0.41
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0005815 microtubule organizing center Database 0.39
Category members Pathway Pathway_1314 REACTOME_KINESINS 0 0.32
Category members GO Category GO:0005871 kinesin complex Database 0.27
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members GO Category GO:0005875 microtubule associated complex Database 0
Category members GO Category GO:0000070 mitotic sister chromatid segregation Database 0


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