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Query: KIF5A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KIF5A 0 2.425 0.000 1.050 -0.312
KIF5A 0 2.425 0.000 1.050 0.018 0.333 0.082

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KIF5A Ubiquitylation K10 0.306 0.853 _(ac)ADLAECNIK(gl)VMCR_
KIF5A Ubiquitylation K656 0.402 0.839 _SLTEYLQNVEQK(gl)KR_
KIF5A Ubiquitylation K657 0.839 _SLTEYLQNVEQK(gl)KR_
KIF5A Ubiquitylation K222 -0.686 -0.137 _QENTQTEQK(gl)LSGK_
KIF5A Ubiquitylation K256 0.392 _TGAEGAVLDEAKNINK(gl)_
KIF5A Ubiquitylation K420 -0.933 _RK(gl)CEEEIAK_

Background Information for KIF5A:


Pubmed-KIF5A »
Uniprot-KIF5A »
Biogrid-KIF5A »
ProteomicsDB-KIF5A »

Tumorportal-KIF5A »
COSMIC-KIF5A »
GenomeRNAi-KIF5A »
Genecards-KIF5A


Protein-protein Interactions for KIF5A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait VPS26B Cat. description Hein, Mann, Cell 2015
Category members IP bait BMP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRNA9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COG6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYCL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRAK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KIF5A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Kinesin_motor_dom IPR001752 0
Category members Prefoldin IPR009053 0


Protein complexes (CORUM database) featuring KIF5A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KIF5A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0007018 microtubule-based movement Database 0.75
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members Pathway Pathway_1314 REACTOME_KINESINS 0 0.32
Category members GO Category GO:0005871 kinesin complex Database 0.27
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0003774 motor activity Database 0.2
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members GO Category GO:0008219 cell death Database 0.08
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07


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