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Query: KIF21A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KIF21A 0 2.135 1.800 -1.170

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KIF21A Ubiquitylation K1058 0.698 0.952 _GLQAAQK(gl)EAQIK_
KIF21A Phosphorylation S853 0.472 0.012 _KLS(ph)SSDAPAQDTGSSAAAVETDASR_
KIF21A Phosphorylation S1239 -0.523 -0.355 _KIPEPS(ph)PVTR_
KIF21A Phosphorylation S1212 -0.653 -0.788 _EKELS(ph)PPPGLPSK_
KIF21A Phosphorylation T862 0.469 _KLSSSDAPAQDT(ph)GSSAAAVETDASR_

Background Information for KIF21A:


Pubmed-KIF21A »
Uniprot-KIF21A »
Biogrid-KIF21A »
ProteomicsDB-KIF21A »

Tumorportal-KIF21A »
COSMIC-KIF21A »
GenomeRNAi-KIF21A »
Genecards-KIF21A


Protein-protein Interactions for KIF21A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF21A Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF21B Cat. description Hein, Mann, Cell 2015
Category members IP bait P4HA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KIF21A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members P-loop_NTPase IPR027417 2.83
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members G-protein_beta_WD-40_rep IPR020472 0.12
Category members Kinesin_motor_dom IPR001752 0
Category members Prefoldin IPR009053 0


Protein complexes (CORUM database) featuring KIF21A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KIF21A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0007018 microtubule-based movement Database 0.75
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members GO Category GO:0005871 kinesin complex Database 0.27
Category members Disease phenotype Congenital_fibrosis_of_extraocular_muscles Congenital fibrosis of extraocular muscles Database 0


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