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Query: KIF18A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KIF18A 0 -0.739 0.900 -1.020 -0.544

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KIF18A Phosphorylation S613 -0.249 _RLS(ph)GPLHTLGIPPGPNCTPAQGSR_
KIF18A Phosphorylation S413 -0.444 -0.279 _KLQVYEGGGQPPPQDLPGS(ph)PK_
KIF18A Ubiquitylation K531 0.498 _QLALK(gl)VLCVAQR_

Background Information for KIF18A:


Pubmed-KIF18A »
Uniprot-KIF18A »
Biogrid-KIF18A »
ProteomicsDB-KIF18A »

Tumorportal-KIF18A »
COSMIC-KIF18A »
GenomeRNAi-KIF18A »
Genecards-KIF18A


Protein-protein Interactions for KIF18A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC16 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC26 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIAA1279 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF18A Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF18B Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIAA1279 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CC Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KIF18A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Kinesin_motor_dom IPR001752 0


Protein complexes (CORUM database) featuring KIF18A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KIF18A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members GO Category GO:0003779 actin binding Database 5.41
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0043130 ubiquitin binding Database 1.22
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0007018 microtubule-based movement Database 0.75
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members GO Category GO:0051010 microtubule plus-end binding Database 0.47
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0005815 microtubule organizing center Database 0.39
Category members GO Category GO:0001726 ruffle Database 0.33
Category members Pathway Pathway_1314 REACTOME_KINESINS 0 0.32
Category members GO Category GO:0005871 kinesin complex Database 0.27
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members GO Category GO:0007080 mitotic metaphase plate congression Database 0.04
Category members GO Category GO:0005828 kinetochore microtubule Database 0
Category members GO Category GO:0005901 caveola Database 0
Category members GO Category GO:0007019 microtubule depolymerization Database 0
Category members GO Category GO:0008574 plus-end-directed microtubule motor activity Database 0


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