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Query: KIF11

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KIF11 1 1.891
KIF11 1 1.891 0.070 -0.504 0.140

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KIF11 Ubiquitylation K952 2.074 _EHLLDQLK(gl)R_
KIF11 Ubiquitylation K712 0.374 0.266 _QCGNLTEDLK(gl)TIK_
KIF11 Phosphorylation T925 -0.275 0.012 _LDIPTGT(ph)TPQRK_
KIF11 Phosphorylation T926 -0.432 -0.040 _LDIPTGTT(ph)PQR_
KIF11 Ubiquitylation K715 -0.699 _TIK(gl)QTHSQELCK_
KIF11 Ubiquitylation K1034 -0.839 _SK(gl)VEETTEHLVTK_

Background Information for KIF11:





Protein-protein Interactions for KIF11

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC13 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF11 Cat. description Hein, Mann, Cell 2015
Category members IP bait TACC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait C17orf59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C4orf6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CASP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPERT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TFDP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KIF11

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Kinesin_motor_dom IPR001752 0


Protein complexes (CORUM database) featuring KIF11

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2183 Kaiso-NCOR complex Database 0


Categories featuring KIF11

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0007018 microtubule-based movement Database 0.75
Category members GO Category GO:0005876 spindle microtubule Database 0.68
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members GO Category GO:0005819 spindle Database 0.41
Category members GO Category GO:0007052 mitotic spindle organization Database 0.41
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0000922 spindle pole Database 0.35
Category members Pathway Pathway_1314 REACTOME_KINESINS 0 0.32
Category members GO Category GO:0005871 kinesin complex Database 0.27
Category members GO Category GO:0007100 mitotic centrosome separation Database 0.17
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members GO Category GO:0007051 spindle organization Database 0.04


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