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Query: KDSR

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KDSR 0 -1.706 0.240 -0.260 -0.411 0.471

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KDSR Ubiquitylation K161 0.268 _AVITTMK(gl)ER_
KDSR Ubiquitylation K246 -2.034 -0.910 _LISETTSVCK(gl)PEQVAK_

Background Information for KDSR:





Protein-protein Interactions for KDSR

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ERCC6L Cat. description Hein, Mann, Cell 2015
Category members IP bait IPPK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait REEP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RELL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KDSR

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DH_sc/Rdtase_SDR IPR002198 0
Category members Glc/ribitol_DH IPR002347 0
Category members DHB_DH IPR003560 0
Category members PKS_KR IPR013968 0


Protein complexes (CORUM database) featuring KDSR

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KDSR

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_127 KEGG_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_128 REACTOME_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_498 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS 0 0
Category members GO Category GO:0006665 sphingolipid metabolic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0030148 sphingolipid biosynthetic process Database 0


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