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Query: IWS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IWS1 1 0.838 -0.490 0.330 0.160 1.997 -2.731 0.440

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IWS1 Phosphorylation S377 -0.650 0.600 _MDS(ph)DEDEKEGEEEK_
IWS1 Phosphorylation S248 -1.222 -0.169 _IS(ph)DSESEDPPR_
IWS1 Phosphorylation S398 -1.092 -0.336 _AAVLS(ph)DSEDEEK_
IWS1 Phosphorylation S313 0.042 _GPAS(ph)DSETEDASR_

Background Information for IWS1:


Pubmed-IWS1 »
Uniprot-IWS1 »
Biogrid-IWS1 »
ProteomicsDB-IWS1 »

Tumorportal-IWS1 »
COSMIC-IWS1 »
GenomeRNAi-IWS1 »
Genecards-IWS1


Protein-protein Interactions for IWS1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC88A Cat. description Hein, Mann, Cell 2015
Category members IP bait CTR9 Cat. description Hein, Mann, Cell 2015
Category members IP bait IWS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LLGL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPRD1B Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SUPT5H Cat. description Hein, Mann, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IWS1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TFIIS_N IPR017923 0.01


Protein complexes (CORUM database) featuring IWS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IWS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0051028 mRNA transport Database 1.7
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0010793 regulation of mRNA export from nucleus Database 0
Category members GO Category GO:0050684 regulation of mRNA processing Database 0


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