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Query: ITGB3BP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ITGB3BP 0 -0.280 -0.290 0.460

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ITGB3BP Ubiquitylation K145 -0.740 _ELMTK(gl)VNK_
ITGB3BP Ubiquitylation K154 -0.977 _LFEK(gl)STGLPHK_

Background Information for ITGB3BP:


Pubmed-ITGB3BP »
Uniprot-ITGB3BP »
Biogrid-ITGB3BP »
ProteomicsDB-ITGB3BP »

Tumorportal-ITGB3BP »
COSMIC-ITGB3BP »
GenomeRNAi-ITGB3BP »
Genecards-ITGB3BP


Protein-protein Interactions for ITGB3BP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CENPH Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPO Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPQ Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGB3BP Cat. description Hein, Mann, Cell 2015
Category members IP bait MLF1IP Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPO Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CENPP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CNBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MECP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLF1IP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ITGB3BP
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring ITGB3BP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1179 CENP-A NAC-CAD complex Database 0


Categories featuring ITGB3BP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0034080 CENP-A containing nucleosome assembly at centromere Database 4.75
Category members Pathway Pathway_1281 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 0 4.19
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0007067 mitosis Database 2.23
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members Pathway Pathway_309 ST_INTEGRIN_SIGNALING_PATHWAY 0 1.35
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members Pathway Pathway_739 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 0 0.23
Category members Pathway Pathway_779 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE 0 0.2
Category members Pathway Pathway_799 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS 0 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007165 signal transduction Database 0


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