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Query: IST1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IST1 0 -3.403 1.130 -0.850 0.443 -1.841 -1.484

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IST1 Ubiquitylation K140 0.255 -0.333 _IVADQLCAK(gl)YSK_
IST1 Ubiquitylation K164 -0.495 -0.696 _LMHK(gl)LSVEAPPK_
IST1 Ubiquitylation K20 -0.587 _(ac)MLGSGFK(gl)AER_
IST1 Ubiquitylation K61 -0.579 _EIADYLAAGK(gl)DER_
IST1 Ubiquitylation K147 -0.470 _EYGK(gl)LCR_

Background Information for IST1:





Protein-protein Interactions for IST1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP6AP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP55 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait CNOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait MYL12A;MYL12B Cat. description Hein, Mann, Cell 2015
Category members IP bait PTPN23 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait SPAST Cat. description Hein, Mann, Cell 2015
Category members IP bait TFG Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TSG101 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS4B Cat. description Hein, Mann, Cell 2015


Protein Domains in IST1

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring IST1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IST1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members GO Category GO:0051301 cell division Database 1.15
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0005793 endoplasmic reticulum-Golgi intermediate compartment Database 0.74
Category members GO Category GO:0008104 protein localization Database 0.5
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17
Category members GO Category GO:0000910 cytokinesis Database 0.15
Category members GO Category GO:0009838 abscission Database 0
Category members GO Category GO:0019076 viral release from host cell Database 0
Category members GO Category GO:0045862 positive regulation of proteolysis Database 0
Category members GO Category GO:0048672 positive regulation of collateral sprouting Database 0


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