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Query: IQSEC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IQSEC1 0 4.861 -1.780 2.490

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IQSEC1 Phosphorylation S926 1.364 1.007 _RSS(ph)AGSLESNVEGSIISSPHM(ox)R_
IQSEC1 Phosphorylation S924 0.327 _SALS(ph)SSLRDLSEAGVHH_
IQSEC1 Phosphorylation S498 0.064 0.312 _NS(ph)WDSPAFSNDVIR_
IQSEC1 Phosphorylation S166 0.273 0.206 _MQFS(ph)FEGPEK_
IQSEC1 Phosphorylation S911 -0.588 0.135 _RSALSSS(ph)LRDLSEAGK_
IQSEC1 Phosphorylation S925 0.548 _SALSS(ph)SLRDLSEAGVHH_

Background Information for IQSEC1:


Pubmed-IQSEC1 »
Uniprot-IQSEC1 »
Biogrid-IQSEC1 »
ProteomicsDB-IQSEC1 »

Tumorportal-IQSEC1 »
COSMIC-IQSEC1 »
GenomeRNAi-IQSEC1 »
Genecards-IQSEC1


Protein-protein Interactions for IQSEC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SRPR Cat. description Hein, Mann, Cell 2015
Category members IP bait APBA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM196A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLLT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P4HA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SKP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IQSEC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PH_domain IPR001849 0.14
Category members IQ_motif_EF-hand-BS IPR000048 0
Category members Sec7_dom IPR000904 0


Protein complexes (CORUM database) featuring IQSEC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IQSEC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members Pathway Pathway_992 PID_ARF6_PATHWAY 0 0.46
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0005086 ARF guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0032012 regulation of ARF protein signal transduction Database 0


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