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Query: INTS2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
INTS2 4 8.706 -1.660 2.780 2.171 1.910 2.253 -0.910 0.697

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
INTS2 Ubiquitylation K255 -0.069 -0.127 _FLCK(gl)MNPSQALK_
INTS2 Ubiquitylation K263 -0.339 _MNPSQALK(gl)VR_
INTS2 Ubiquitylation K68 -0.467 _MALCAPADQSQSWAQDK(gl)K_
INTS2 Ubiquitylation K69 -0.467 _MALCAPADQSQSWAQDK(gl)K_

Background Information for INTS2:


Pubmed-INTS2 »
Uniprot-INTS2 »
Biogrid-INTS2 »
ProteomicsDB-INTS2 »

Tumorportal-INTS2 »
COSMIC-INTS2 »
GenomeRNAi-INTS2 »
Genecards-INTS2


Protein-protein Interactions for INTS2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CA Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2R1A Cat. description Hein, Mann, Cell 2015
Category members IP bait VWA9 Cat. description Hein, Mann, Cell 2015
Category members IP bait APLNR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD274 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKKL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPEP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM174A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC15A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in INTS2
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring INTS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1155 Integrator-RNAPII complex Database 5.97
Category members Corum 1153 Integrator complex Database 4.67
Category members Corum 1154 DSS1 complex Database 1.97


Categories featuring INTS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0032039 integrator complex Database 4.79
Category members GO Category GO:0016180 snRNA processing Database 4.67
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0005622 intracellular Database 0.32


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