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Query: INTS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
INTS1 3 5.382 -1.170 1.510
INTS1 3 5.382 -1.170 1.510 -1.346 1.728 1.884 -0.472 0.079

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
INTS1 Phosphorylation S1531 1.094 1.777 _S(ph)SPEQPIGQGR_
INTS1 Phosphorylation S1532 1.094 1.777 _S(ph)SPEQPIGQGR_
INTS1 Ubiquitylation K327 -0.872 _DASINFKAK(gl)_
INTS1 Phosphorylation S435 -1.397 _VAGDLGAGSSPHPSLTEEEDSQTELLIAEEKLS(ph)PEQEGQLMPR_
INTS1 Ubiquitylation K1530 -4.131 _DSTEAPKPK(gl)SSPEQPIGQGR_
INTS1 Phosphorylation S210 -0.416 _LSS(ph)TPPLSALGR_

Background Information for INTS1:


Pubmed-INTS1 »
Uniprot-INTS1 »
Biogrid-INTS1 »
ProteomicsDB-INTS1 »

Tumorportal-INTS1 »
COSMIC-INTS1 »
GenomeRNAi-INTS1 »
Genecards-INTS1


Protein-protein Interactions for INTS1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PPP2R1A Cat. description Hein, Mann, Cell 2015
Category members IP bait ALDH3A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait APLNR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ILVBL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INTS12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPY2R Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OPRM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TGOLN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in INTS1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring INTS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1155 Integrator-RNAPII complex Database 5.97
Category members Corum 1153 Integrator complex Database 4.67


Categories featuring INTS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0032039 integrator complex Database 4.79
Category members GO Category GO:0016180 snRNA processing Database 4.67
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0001832 blastocyst growth Database 0.83
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0001833 inner cell mass cell proliferation Database 0
Category members GO Category GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0


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