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Query: INPP5E

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
INPP5E 1 1.287 2.910 -1.420

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
INPP5E Phosphorylation S99 0.650 0.637 _FRGS(ph)QEDLEAR_

Background Information for INPP5E:


Pubmed-INPP5E »
Uniprot-INPP5E »
Biogrid-INPP5E »
ProteomicsDB-INPP5E »

Tumorportal-INPP5E »
COSMIC-INPP5E »
GenomeRNAi-INPP5E »
Genecards-INPP5E


Protein-protein Interactions for INPP5E
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in INPP5E
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members IPPc IPR000300 0.1
Category members Endo/exonuclease/phosphatase IPR005135 0


Protein complexes (CORUM database) featuring INPP5E
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring INPP5E
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0046855 inositol phosphate dephosphorylation Database 0.58
Category members Pathway Pathway_501 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE 0 0.46
Category members GO Category GO:0046856 phosphatidylinositol dephosphorylation Database 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_106 KEGG_INOSITOL_PHOSPHATE_METABOLISM 0 0.28
Category members GO Category GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity Database 0.23
Category members Disease phenotype Joubert_syndrome_with_ocular_defect Joubert syndrome with ocular defect Database 0.08
Category members Disease phenotype JOUBERT_SYNDROME JOUBERT SYNDROME Database 0.07
Category members GO Category GO:0006661 phosphatidylinositol biosynthetic process Database 0.06
Category members Pathway Pathway_103 REACTOME_PI_METABOLISM 0 0.04
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_488 KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0004445 inositol-polyphosphate 5-phosphatase activity Database 0
Category members GO Category GO:0005930 axoneme Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0008150 biological_process Database 0
Category members GO Category GO:0032580 Golgi cisterna membrane Database 0
Category members GO Category GO:0046488 phosphatidylinositol metabolic process Database 0


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