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Query: HSD17B6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HSD17B6 0 0.134 -0.450 0.040

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HSD17B6 Ubiquitylation K64 0.094 _VLAACLTEK(gl)GAEQLR_

Background Information for HSD17B6:


Pubmed-HSD17B6 »
Uniprot-HSD17B6 »
Biogrid-HSD17B6 »
ProteomicsDB-HSD17B6 »

Tumorportal-HSD17B6 »
COSMIC-HSD17B6 »
GenomeRNAi-HSD17B6 »
Genecards-HSD17B6


Protein-protein Interactions for HSD17B6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP2B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSD17B6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HSD17B6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DH_sc/Rdtase_SDR IPR002198 0
Category members Glc/ribitol_DH IPR002347 0


Protein complexes (CORUM database) featuring HSD17B6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HSD17B6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0006710 androgen catabolic process Database 0.08
Category members GO Category GO:0009055 electron carrier activity Database 0.02
Category members Pathway Pathway_89 KEGG_STEROID_HORMONE_BIOSYNTHESIS 0 0
Category members GO Category GO:0004303 estradiol 17-beta-dehydrogenase activity Database 0
Category members GO Category GO:0004745 retinol dehydrogenase activity Database 0
Category members GO Category GO:0006702 androgen biosynthetic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0047035 testosterone dehydrogenase (NAD+) activity Database 0


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