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Query: HPS6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HPS6 0 -2.942 0.100 -0.400

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HPS6 Ubiquitylation K239 -1.919 -1.023 _LGLSYSK(gl)SLNPGR_
HPS6 Ubiquitylation K546 -1.124 _SQAPPDVWKK(gl)_
HPS6 Ubiquitylation K545 -1.483 _SQAPPDVWK(gl)K_

Background Information for HPS6:


Pubmed-HPS6 »
Uniprot-HPS6 »
Biogrid-HPS6 »
ProteomicsDB-HPS6 »

Tumorportal-HPS6 »
COSMIC-HPS6 »
GenomeRNAi-HPS6 »
Genecards-HPS6


Protein-protein Interactions for HPS6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HPS6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HPS6
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring HPS6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 12 BLOC-2 (biogenesis of lysosome-related organelles complex 2) Database 0.18
Category members Corum 654 BLOC1-BLOC2 complex Database 0


Categories featuring HPS6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members Disease phenotype Hermansky-Pudlak_syndrome_without_pulmonary_fibrosis Hermansky-Pudlak syndrome without pulmonary fibrosis Database 0.18
Category members GO Category GO:0031084 BLOC-2 complex Database 0.18
Category members GO Category GO:0006996 organelle organization Database 0
Category members GO Category GO:0030318 melanocyte differentiation Database 0
Category members GO Category GO:0043473 pigmentation Database 0


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