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Query: HPS5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HPS5 0 -1.032 0.900 -0.830

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HPS5 Phosphorylation S534 -1.032 _SPS(ph)PLVSLQAVK_

Background Information for HPS5:





Protein-protein Interactions for HPS5

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BLM Cat. description Hein, Mann, Cell 2015
Category members IP bait BUB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC22 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD14 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC26 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP135 Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIFC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LCK Cat. description Hein, Mann, Cell 2015
Category members IP bait MAGOH;MAGOHB Cat. description Hein, Mann, Cell 2015
Category members IP bait PAPSS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PHKG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2R1A Cat. description Hein, Mann, Cell 2015
Category members IP bait PSMB4 Cat. description Hein, Mann, Cell 2015
Category members IP bait RASSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait AARSD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HPS6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCL1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HPS5

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39


Protein complexes (CORUM database) featuring HPS5

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 12 BLOC-2 (biogenesis of lysosome-related organelles complex 2) Database 0.18
Category members Corum 654 BLOC1-BLOC2 complex Database 0


Categories featuring HPS5

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members Disease phenotype Hermansky-Pudlak_syndrome_without_pulmonary_fibrosis Hermansky-Pudlak syndrome without pulmonary fibrosis Database 0.18
Category members GO Category GO:0031084 BLOC-2 complex Database 0.18
Category members GO Category GO:0006996 organelle organization Database 0
Category members GO Category GO:0043473 pigmentation Database 0


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