bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: HNRNPH1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HNRNPH1 0 2.479 -1.090 0.570
HNRNPH1 0 2.479 -1.090 0.570 -0.126 -1.017 -0.294

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HNRNPH1 Ubiquitylation K185 0.405 0.793 _YIEIFK(gl)SSR_
HNRNPH1 Phosphorylation T100 0.088 0.516 _HT(ph)GPNSPDTANDGFVR_
HNRNPH1 Phosphorylation T100 0.088 0.516 _HT(ph)GPNSPDTANDGFVR_
HNRNPH1 Phosphorylation S104 0.321 0.267 _HTGPNS(ph)PDTANDGFVR_
HNRNPH1 Phosphorylation S104 0.321 0.267 _HTGPNS(ph)PDTANDGFVR_
HNRNPH1 Phosphorylation S310 0.125 0.147 _ATENDIYNFFS(ph)PLNPVR_
HNRNPH1 Ubiquitylation K35 -0.212 -0.178 _FFSDCK(gl)IQNGAQGIR_

Background Information for HNRNPH1:


Pubmed-HNRNPH1 »
Uniprot-HNRNPH1 »
Biogrid-HNRNPH1 »
ProteomicsDB-HNRNPH1 »

Tumorportal-HNRNPH1 »
COSMIC-HNRNPH1 »
GenomeRNAi-HNRNPH1 »
Genecards-HNRNPH1


Protein-protein Interactions for HNRNPH1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPF Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait NDC80 Cat. description Hein, Mann, Cell 2015
Category members IP bait NAGK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLOD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HNRNPH1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members Znf_CHHC IPR012996 0


Protein complexes (CORUM database) featuring HNRNPH1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1181 C complex spliceosome Database 2.39
Category members Corum 1332 Large Drosha complex Database 0.08
Category members Corum 3082 DGCR8 multiprotein complex Database 0.07
Category members Corum 1287 HNRPF-HNRPH1 complex Database 0
Category members Corum 1288 DCS complex (PTBP1, PTBP2, HNRPH1, HNRPF) Database 0


Categories featuring HNRNPH1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0006396 RNA processing Database 0.17
Category members Disease phenotype Precursor_T-cell_acute_lymphoblastic_leukemia Precursor T-cell acute lymphoblastic leukemia Database 0
Category members GO Category GO:0008266 poly(U) RNA binding Database 0
Category members GO Category GO:0043484 regulation of RNA splicing Database 0


.

© Copyright Svejstrup Laboratory 2015