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Query: HNRNPA3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HNRNPA3 1 4.156 -2.410 4.630 -0.068 -1.744 -0.753 -1.094 -0.708
HNRNPA3 1 4.156 -2.410 4.630 0.142 -0.823 -0.034

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HNRNPA3 Phosphorylation S366 0.271 _SSGS(ph)PYGGGYGS(ph)GGGSGGYGSR_
HNRNPA3 Phosphorylation S356 0.109 _SS(ph)GSPYGGGYGSGGGS(ph)GGYGSR_
HNRNPA3 Phosphorylation S370 0.109 _SS(ph)GSPYGGGYGSGGGS(ph)GGYGSR_
HNRNPA3 Phosphorylation S358 0.330 0.068 _SSGS(ph)PYGGGYGSGGGSGGYGSR_
HNRNPA3 Ubiquitylation K204 -0.224 _ALSK(gl)QEMQSAGSQR_
HNRNPA3 Phosphorylation S14 -2.193 -1.422 _(ac)M(ox)EVKPPPGRPQPDS(ph)GR_
HNRNPA3 Ubiquitylation K4 -2.471 -1.735 _(ac)MEVK(gl)PPPGRPQPDSGRR_
HNRNPA3 Ubiquitylation K73 -0.883 _WGTLTDCVVMRDPQTK(gl)R_
HNRNPA3 Ubiquitylation K126 0.379 _EDSVKPGAHLTVK(gl)K_
HNRNPA3 Ubiquitylation K148 0.809 _DYFEK(gl)YGK_
HNRNPA3 Ubiquitylation K151 0.559 _YGK(gl)IETIEVMEDR_

Background Information for HNRNPA3:


Pubmed-HNRNPA3 »
Uniprot-HNRNPA3 »
Biogrid-HNRNPA3 »
ProteomicsDB-HNRNPA3 »

Tumorportal-HNRNPA3 »
COSMIC-HNRNPA3 »
GenomeRNAi-HNRNPA3 »
Genecards-HNRNPA3


Protein-protein Interactions for HNRNPA3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FUS Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA3 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPH2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TAF15 Cat. description Hein, Mann, Cell 2015


Protein Domains in HNRNPA3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members HnRNPA1 IPR021662 0


Protein complexes (CORUM database) featuring HNRNPA3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1181 C complex spliceosome Database 2.39


Categories featuring HNRNPA3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0003676 nucleic acid binding Database 0.83


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