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Query: HJURP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HJURP 1 0.484 1.460 -0.870

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HJURP Phosphorylation S473 0.215 2.129 _GGPAS(ph)PGGLQGLETR_
HJURP Phosphorylation S486 -0.195 -0.322 _RLS(ph)LPSSK_
HJURP Ubiquitylation K375 -0.763 _LDPSWK(gl)ER_
HJURP Ubiquitylation K278 -1.097 -0.856 _LLSTK(gl)PSSIISTK_
HJURP Ubiquitylation K332 -1.227 _ENFIPCSEPVK(gl)GTGALR_

Background Information for HJURP:





Protein-protein Interactions for HJURP

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CENPA Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HJURP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HJURP

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HJURP_C IPR022102 0


Protein complexes (CORUM database) featuring HJURP

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HJURP

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members GO Category GO:0034080 CENP-A containing nucleosome assembly at centromere Database 4.75
Category members Pathway Pathway_1281 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 0 4.19
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0042393 histone binding Database 0.94
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members GO Category GO:0007059 chromosome segregation Database 0.13
Category members GO Category GO:0043254 regulation of protein complex assembly Database 0
Category members GO Category GO:0051101 regulation of DNA binding Database 0


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