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Query: HIST2H2BF

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HIST2H2BF 1 2.225
HIST2H2BF 1 2.225 -0.763 -0.031 0.617

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HIST2H2BF Ubiquitylation K44 1.903 _ESYSVYVYK(gl)VLK_
HIST2H2BF Ubiquitylation K47 0.349 1.603 _VLK(gl)QVHPDTGISSK_
HIST2H2BF Ubiquitylation K117 0.346 1.538 _HAVSEGTK(gl)AVTK_
HIST2H2BF Ubiquitylation K109 0.117 0.362 _LLLPGELAK(gl)HAVSEGTK_
HIST2H2BF Ubiquitylation K121 -0.997 0.088 _AVTK(gl)YTSSK_
HIST2H2BF Ubiquitylation K6 -1.103 -0.827 _PDPAK(gl)SAPAPK_
HIST2H2BF Ubiquitylation K35 -0.211 _SRK(gl)ESYSVYVYK_
HIST2H2BF Ubiquitylation K86 0.468 _LAHYNK(gl)R_

Background Information for HIST2H2BF:


Pubmed-HIST2H2BF »
Uniprot-HIST2H2BF »
Biogrid-HIST2H2BF »
ProteomicsDB-HIST2H2BF »

Tumorportal-HIST2H2BF »
COSMIC-HIST2H2BF »
GenomeRNAi-HIST2H2BF »
Genecards-HIST2H2BF


Protein-protein Interactions for HIST2H2BF
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MECP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL10A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HIST2H2BF
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring HIST2H2BF
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HIST2H2BF
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members GO Category GO:0000786 nucleosome Database 2.41
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_889 KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 0 0.9
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18


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