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Query: HIST2H2AC

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HIST2H2AC 0 1.293 1.060 -0.910
HIST2H2AC 0 1.293 1.060 -0.910 -0.506 0.278
HIST2H2AC 0 1.293 1.060 -0.910 -0.438 0.112 0.401

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HIST2H2AC Ubiquitylation K96 0.928 0.630 _NDEELNK(gl)LLGK_
HIST2H2AC Ubiquitylation K120 0.042 0.241 _VTIAQGGVLPNIQAVLLPKK(gl)TESHHK_
HIST2H2AC Ubiquitylation K120 0.034 0.241 _VTIAQGGVLPNIQAVLLPKK(gl)TESHK_
HIST2H2AC Ubiquitylation K119 0.219 0.142 _VTIAQGGVLPNIQAVLLPK(gl)KTESHHK_
HIST2H2AC Ubiquitylation K119 0.016 0.109 _VTIAQGGVLPNIQAVLLPK(gl)K_
HIST2H2AC Ubiquitylation K126 0.224 _VTIAQGGVLPNIQAVLLPKKTESHHK(gl)_
HIST2H2AC Ubiquitylation K125 0.065 _VTIAQGGVLPNIQAVLLPKKTESHK(gl)_

Background Information for HIST2H2AC:


Pubmed-HIST2H2AC »
Uniprot-HIST2H2AC »
Biogrid-HIST2H2AC »
ProteomicsDB-HIST2H2AC »

Tumorportal-HIST2H2AC »
COSMIC-HIST2H2AC »
GenomeRNAi-HIST2H2AC »
Genecards-HIST2H2AC


Protein-protein Interactions for HIST2H2AC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ALDH3A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C13orf31 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1683 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LINGO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAP3K13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MMP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HIST2H2AC
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring HIST2H2AC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HIST2H2AC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_351 REACTOME_RNA_POL_I_TRANSCRIPTION 0 8.31
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members Pathway Pathway_884 REACTOME_MEIOTIC_SYNAPSIS 0 7.46
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members Pathway Pathway_875 REACTOME_MEIOSIS 0 6.39
Category members Pathway Pathway_1281 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 0 4.19
Category members Pathway Pathway_1312 REACTOME_PACKAGING_OF_TELOMERE_ENDS 0 4.09
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members Pathway Pathway_328 REACTOME_TELOMERE_MAINTENANCE 0 3.74
Category members Pathway Pathway_874 REACTOME_MEIOTIC_RECOMBINATION 0 3.7
Category members Pathway Pathway_1139 REACTOME_RNA_POL_I_PROMOTER_OPENING 0 3.56
Category members GO Category GO:0000786 nucleosome Database 2.41
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_889 KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 0 0.9
Category members Pathway Pathway_920 REACTOME_AMYLOIDS 0 0.68
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18


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