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Query: HIST2H2AB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HIST2H2AB 0 1.705 -0.550 0.800
HIST2H2AB 0 1.705 -0.550 0.800 0.399 0.905 -0.117 -0.109

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HIST2H2AB Ubiquitylation K119 -0.262 _LLGGVTIAQGGVLPNIQAVLLPK(gl)K_
HIST2H2AB Ubiquitylation K120 -0.173 _LLGGVTIAQGGVLPNIQAVLLPKK(gl)_

Background Information for HIST2H2AB:


Pubmed-HIST2H2AB »
Uniprot-HIST2H2AB »
Biogrid-HIST2H2AB »
ProteomicsDB-HIST2H2AB »

Tumorportal-HIST2H2AB »
COSMIC-HIST2H2AB »
GenomeRNAi-HIST2H2AB »
Genecards-HIST2H2AB


Protein-protein Interactions for HIST2H2AB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait APLF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPATCH4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1T Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H2BA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KBTBD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAK16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAA40 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAP1L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PARL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PEF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRDM5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL37A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPAST Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WBSCR22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait XPC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB38 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZCRB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF398 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF428 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF491 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF512 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HIST2H2AB
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring HIST2H2AB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HIST2H2AB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members GO Category GO:0000786 nucleosome Database 2.41
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_889 KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 0 0.9
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18


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