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Query: HINT1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HINT1 0 -0.028 -0.300 -0.170

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HINT1 Ubiquitylation K7 -0.290 -0.277 _(ac)ADEIAK(gl)AQVAR_
HINT1 Ubiquitylation K30 -0.546 _EIPAK(gl)IIFEDDR_
HINT1 Ubiquitylation K92 0.420 _CAADLGLNK(gl)GYR_

Background Information for HINT1:


Pubmed-HINT1 »
Uniprot-HINT1 »
Biogrid-HINT1 »
ProteomicsDB-HINT1 »

Tumorportal-HINT1 »
COSMIC-HINT1 »
GenomeRNAi-HINT1 »
Genecards-HINT1


Protein-protein Interactions for HINT1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTL6A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HINT1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Histidine_triad_HIT IPR001310 0
Category members HIT-like IPR011146 0


Protein complexes (CORUM database) featuring HINT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HINT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0005080 protein kinase C binding Database 0.04
Category members GO Category GO:0000118 histone deacetylase complex Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007165 signal transduction Database 0


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