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Query: HELZ

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HELZ 0 0.262 1.270 -1.140 -0.822

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HELZ Ubiquitylation K18 0.536 _SCEQACESLK(gl)R_
HELZ Ubiquitylation K107 0.446 _GK(gl)LQPVSTILAK_
HELZ Phosphorylation S1764 0.380 0.066 _RIS(ph)SSSVQPCSEEVSTPQDSLAQCK_
HELZ Phosphorylation S1739 0.482 -0.099 _TVS(ph)SSSLPSLEEYEPR_
HELZ Ubiquitylation K1097 -0.407 _AQLEALELKK(gl)_
HELZ Phosphorylation S1615 -0.658 -0.677 _S(ph)PPAVPSPPSSTDHSSHFSNFNDNSR_
HELZ Phosphorylation T1164 -2.116 -1.128 _AYT(ph)PPPPLGPHPNLGK_
HELZ Ubiquitylation K453 -1.692 _SLTK(gl)SNYQSR_

Background Information for HELZ:


Pubmed-HELZ »
Uniprot-HELZ »
Biogrid-HELZ »
ProteomicsDB-HELZ »

Tumorportal-HELZ »
COSMIC-HELZ »
GenomeRNAi-HELZ »
Genecards-HELZ


Protein-protein Interactions for HELZ
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait LGALS3BP Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait BCAT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CELA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CELA3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLASRP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ESRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNB2L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HCFC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIGT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBFOX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THSD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HELZ
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members UvrD-like_ATP-bd IPR014016 0.05
Category members Znf_CCCH IPR000571 0.03


Protein complexes (CORUM database) featuring HELZ
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HELZ
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0046872 metal ion binding Database 0


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