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Query: HBS1L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HBS1L 0 -0.842 -0.090 0.440 -0.012 -0.490 -1.022

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HBS1L Ubiquitylation K109 -0.809 0.721 _NK(gl)FDVQK_
HBS1L Ubiquitylation K622 -0.479 0.179 _LISVLNK(gl)STGEVTK_
HBS1L Ubiquitylation K143 -1.074 _IAK(gl)GKPVDSQTSR_

Background Information for HBS1L:


Pubmed-HBS1L »
Uniprot-HBS1L »
Biogrid-HBS1L »
ProteomicsDB-HBS1L »

Tumorportal-HBS1L »
COSMIC-HBS1L »
GenomeRNAi-HBS1L »
Genecards-HBS1L


Protein-protein Interactions for HBS1L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DIS3L Cat. description Hein, Mann, Cell 2015
Category members IP bait EXOSC1;RP11 Cat. description Hein, Mann, Cell 2015
Category members IP bait EXOSC9 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait CACNG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOSC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOSC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOSC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOSC8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GCHFR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HBS1L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ISOC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JMJD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIN9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MSX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB39B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STK25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HBS1L
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Transl_B-barrel IPR009000 0.24
Category members Transl_elong_EFTu/EF1A_C IPR004160 0.01
Category members Transl_elong_EFTu/EF1A_2 IPR004161 0
Category members Transl_elong_EF1A/Init_IF2_C IPR009001 0


Protein complexes (CORUM database) featuring HBS1L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HBS1L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0003746 translation elongation factor activity Database 0.08
Category members GO Category GO:0007165 signal transduction Database 0


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