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Query: GTPBP3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GTPBP3 0 -0.519 0.070 -0.510

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GTPBP3 Ubiquitylation K474 -0.519 _QSK(gl)DLALAAEALR_
GTPBP3 Ubiquitylation K294 -1.210 _K(gl)PVSIVSPEPGTTR_

Background Information for GTPBP3:





Protein-protein Interactions for GTPBP3

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CPM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPHA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GTPBP3

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members GTP_binding_domain IPR006073 0.59
Category members Small_GTP-bd_dom IPR005225 0.32


Protein complexes (CORUM database) featuring GTPBP3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GTPBP3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Disease phenotype Deafness_aminoglycoside-induced Deafness aminoglycoside-induced Database 0.29
Category members GO Category GO:0006400 tRNA modification Database 0.25
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16


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