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Query: GTPBP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GTPBP1 0 1.232 -1.230 1.510 0.066 -0.099 0.407

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GTPBP1 Phosphorylation S580 0.092 0.174 _LLQTTNNS(ph)PMNSKPQQIK_
GTPBP1 Phosphorylation S25 -1.065 -1.057 _SAMDSPVPASM(ox)FAPEPSS(ph)PGAAR_
GTPBP1 Phosphorylation S24 -1.128 -1.273 _SAMDS(ph)PVPASMFAPEPS(ph)SPGAAR_
GTPBP1 Phosphorylation S12 -1.371 -1.763 _SAM(ox)DS(ph)PVPASM(ox)FAPEPSS(ph)PGAAR_
GTPBP1 Ubiquitylation K467 -0.918 _GGQTASFALKK(gl)_

Background Information for GTPBP1:


Pubmed-GTPBP1 »
Uniprot-GTPBP1 »
Biogrid-GTPBP1 »
ProteomicsDB-GTPBP1 »

Tumorportal-GTPBP1 »
COSMIC-GTPBP1 »
GenomeRNAi-GTPBP1 »
Genecards-GTPBP1


Protein-protein Interactions for GTPBP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHAMP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CIT Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait GSPT1;GSPT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ISOC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VASP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GTPBP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Transl_B-barrel IPR009000 0.24
Category members Transl_elong_EFTu/EF1A_C IPR004160 0.01
Category members Transl_elong_EFTu/EF1A_2 IPR004161 0
Category members Transl_elong_EF1A/Init_IF2_C IPR009001 0


Protein complexes (CORUM database) featuring GTPBP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GTPBP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006955 immune response Database 1.22
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0000177 cytoplasmic exosome (RNase complex) Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0061014 positive regulation of mRNA catabolic process Database 0


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