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Query: GMDS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GMDS 0 -0.928 0.500 -0.210

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GMDS Ubiquitylation K301 -0.928 _TIVWEGK(gl)NENEVGR_

Background Information for GMDS:


Pubmed-GMDS »
Uniprot-GMDS »
Biogrid-GMDS »
ProteomicsDB-GMDS »

Tumorportal-GMDS »
COSMIC-GMDS »
GenomeRNAi-GMDS »
Genecards-GMDS


Protein-protein Interactions for GMDS
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC22 Cat. description Hein, Mann, Cell 2015
Category members IP bait DDB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF2A Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait SHOC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SKA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMAD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TNKS Cat. description Hein, Mann, Cell 2015
Category members IP bait TNKS2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GMDS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIF1AN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPHP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GMDS
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Epimerase_deHydtase_N IPR001509 0
Category members dTDP_dehydrorham_reduct IPR005913 0


Protein complexes (CORUM database) featuring GMDS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GMDS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_58 KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM 0 0.1
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members Pathway Pathway_61 KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM 0 0.04
Category members GO Category GO:0008831 dTDP-4-dehydrorhamnose reductase activity Database 0
Category members GO Category GO:0019673 GDP-mannose metabolic process Database 0
Category members GO Category GO:0042351 'de novo' GDP-L-fucose biosynthetic process Database 0
Category members GO Category GO:0045226 extracellular polysaccharide biosynthetic process Database 0
Category members GO Category GO:0050662 coenzyme binding Database 0


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