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Query: GLS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GLS 0 2.190 -1.790 2.330 0.022 0.557
GLS 0 2.190 -1.790 2.330 0.244 -0.963 -0.089 -0.173

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for GLS:


Pubmed-GLS »
Uniprot-GLS »
Biogrid-GLS »
ProteomicsDB-GLS »

Tumorportal-GLS »
COSMIC-GLS »
GenomeRNAi-GLS »
Genecards-GLS


Protein-protein Interactions for GLS
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACAD9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCL22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HMGCL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUFIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OTC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRMT61B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YBEY Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GLS
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ankyrin_rpt IPR002110 0
Category members Beta-lactam/transpept-like IPR012338 0
Category members Glutaminase IPR015868 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring GLS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GLS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0006541 glutamine metabolic process Database 0.47
Category members GO Category GO:0051289 protein homotetramerization Database 0.44
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members Pathway Pathway_393 KEGG_NITROGEN_METABOLISM 0 0.07
Category members GO Category GO:0001967 suckling behavior Database 0.05
Category members GO Category GO:0007610 behavior Database 0.04
Category members Pathway Pathway_272 KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM 0 0.04
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members Pathway Pathway_135 KEGG_ARGININE_AND_PROLINE_METABOLISM 0 0.01
Category members Pathway Pathway_397 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE 0 0.01
Category members GO Category GO:0006543 glutamine catabolic process Database 0
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members Pathway Pathway_140 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 0 0
Category members Pathway Pathway_17 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 0 0
Category members Pathway Pathway_36 KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION 0 0
Category members Pathway Pathway_390 REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE 0 0
Category members Pathway Pathway_394 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION 0 0
Category members GO Category GO:0002087 regulation of respiratory gaseous exchange by neurological system process Database 0
Category members GO Category GO:0004359 glutaminase activity Database 0
Category members GO Category GO:0006537 glutamate biosynthetic process Database 0
Category members GO Category GO:0007269 neurotransmitter secretion Database 0
Category members GO Category GO:0008652 cellular amino acid biosynthetic process Database 0
Category members GO Category GO:0014047 glutamate secretion Database 0


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