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Query: GFPT1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GFPT1 1 -0.389 2.210 -0.530 1.053

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GFPT1 Phosphorylation S261 0.067 0.314 _VDS(ph)TTCLFPVEEK_
GFPT1 Phosphorylation T262 0.082 0.273 _VDST(ph)TCLFPVEEK_
GFPT1 Ubiquitylation K694 -2.127 _NLAK(gl)SVTVE_
GFPT1 Ubiquitylation K48 0.289 _GYDSAGVGFDGGNDK(gl)DWEANACK_

Background Information for GFPT1:


Pubmed-GFPT1 »
Uniprot-GFPT1 »
Biogrid-GFPT1 »
ProteomicsDB-GFPT1 »

Tumorportal-GFPT1 »
COSMIC-GFPT1 »
GenomeRNAi-GFPT1 »
Genecards-GFPT1


Protein-protein Interactions for GFPT1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GFPT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GFPT1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SIS IPR001347 0.11
Category members GlmS_trans IPR005855 0.11
Category members GATase_dom IPR000583 0.08
Category members Ntn_hydrolases_N IPR029055 0


Protein complexes (CORUM database) featuring GFPT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GFPT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0006987 activation of signaling protein activity involved in unfolded protein response Database 1.26
Category members GO Category GO:0032869 cellular response to insulin stimulus Database 0.63
Category members GO Category GO:0006541 glutamine metabolic process Database 0.47
Category members GO Category GO:0051289 protein homotetramerization Database 0.44
Category members GO Category GO:0006047 UDP-N-acetylglucosamine metabolic process Database 0.3
Category members GO Category GO:0006488 dolichol-linked oligosaccharide biosynthetic process Database 0.28
Category members GO Category GO:0006048 UDP-N-acetylglucosamine biosynthetic process Database 0.27
Category members GO Category GO:0006112 energy reserve metabolic process Database 0.21
Category members GO Category GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity Database 0.11
Category members GO Category GO:0016597 amino acid binding Database 0.11
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members Pathway Pathway_61 KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM 0 0.04
Category members GO Category GO:0009744 response to sucrose Database 0.04
Category members Pathway Pathway_272 KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM 0 0.04
Category members GO Category GO:0006002 fructose 6-phosphate metabolic process Database 0.02
Category members Disease phenotype Congenital_myasthenic_syndromes_with_glycosylation_defect Congenital myasthenic syndromes with glycosylation defect Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0016051 carbohydrate biosynthetic process Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0030246 carbohydrate binding Database 0
Category members GO Category GO:0032868 response to insulin Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0
Category members GO Category GO:0045719 negative regulation of glycogen biosynthetic process Database 0


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