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Query: GAPVD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GAPVD1 1 8.252 0.020 0.200
GAPVD1 1 8.252 0.020 0.200 1.230

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GAPVD1 Ubiquitylation K49 0.127 4.357 _TAWIAK(gl)QQR_
GAPVD1 Phosphorylation S725 0.942 _LQELESCSGLGS(ph)TSDDTDVR_
GAPVD1 Phosphorylation S881 0.898 0.804 _SRS(ph)SDIVSSVR_
GAPVD1 Phosphorylation S882 0.923 0.788 _SRSS(ph)DIVSSVR_
GAPVD1 Phosphorylation S996 0.716 _RTS(ph)PSDGAMANYESTEVMGDGESAHDSPR_
GAPVD1 Phosphorylation S736 -0.170 0.111 _EVS(ph)SRPSTPGLSVVSGISATSEDIPNKIEDLR_
GAPVD1 Phosphorylation S998 0.038 _RTSPS(ph)DGAMANYESTEVMGDGESAHDSPR_
GAPVD1 Phosphorylation S1019 -0.107 _FSTLTDDPS(ph)PR_
GAPVD1 Phosphorylation T741 -0.772 -0.191 _EVSSRPS(ph)T(ph)PGLSVVSGISATSEDIPNKIEDLR_
GAPVD1 Phosphorylation S740 -0.772 -0.417 _EVSSRPS(ph)T(ph)PGLSVVSGISATSEDIPNKIEDLR_
GAPVD1 Phosphorylation S737 -0.540 -0.507 _EVS(ph)S(ph)RPSTPGLSVVSGISATSEDIPNKIEDLR_
GAPVD1 Phosphorylation S466 -1.886 -1.046 _SSSLEM(ox)TPYNTPQLS(ph)PATTPANK_
GAPVD1 Phosphorylation S931 -1.845 -1.294 _ELPPAAAIGATSLVAAPHSSSSSPS(ph)K_
GAPVD1 Phosphorylation S745 -0.339 _EVS(ph)SRPSTPGLS(ph)VVSGISATSEDIPNKIEDLR_
GAPVD1 Ubiquitylation K24 0.600 _LYVNSEK(gl)QLIQR_
GAPVD1 Ubiquitylation K1353 0.121 _LSK(gl)VVTANHR_

Background Information for GAPVD1:


Pubmed-GAPVD1 »
Uniprot-GAPVD1 »
Biogrid-GAPVD1 »
ProteomicsDB-GAPVD1 »

Tumorportal-GAPVD1 »
COSMIC-GAPVD1 »
GenomeRNAi-GAPVD1 »
Genecards-GAPVD1


Protein-protein Interactions for GAPVD1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AXIN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK1D Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK1E Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C1orf111 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSNK1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSNK1D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSNK1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EFHA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGFR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSSK1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GAPVD1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Rho_GTPase_activation_prot IPR008936 0.53
Category members RasGAP IPR001936 0.19
Category members VPS9 IPR003123 0
Category members VPS9_subgr IPR013995 0


Protein complexes (CORUM database) featuring GAPVD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GAPVD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members GO Category GO:0051223 regulation of protein transport Database 0.18
Category members GO Category GO:0005085 guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0032794 GTPase activating protein binding Database 0


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